Citicoline Sodium Powder

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Citicoline (CDP-Choline) is a naturally-occurring compound used in numerous biochemical pathways in the human body. It is especially important for phospholipid synthesis and membrane repair. It has the chemical formula C14H27N4O11P2+ and a molecular mass of 488.32 g/mol.

Citicoline (CDP-Choline) Benefits and Uses

Citicoline plays an important role in many biochemical systems in the human body. It is especially important as a methyl-group donator, a cofactor for a variety of enzyme systems, and for phospholipid synthesis. Anecdotally, it may have similar effects to other Nootropic compounds.

Citicoline (CDP-Choline) is known by a number of alternative names, including:

  • Cytidine diphosphate-choline
  • Cytidine 5′-diphosphocholine
  • Cytidine diphosphate choline

Scientific Consensus

Citicoline is a brain chemical that is taken for its Nootropic-like effects to support healthy cognition. It is considered possibly safe for use by most people when taken at the recommended serving size for up to 90 days.

Some people have reported adverse effects like difficulty sleeping, headache, diarrhoea, high or low blood pressure, nausea, blurred vision and chest pain. Further research is required to fully understand the significance of the effects and adverse effects of CDP-Choline.

Warning: There is not enough research about the safety of CDP Choline for pregnant and breastfeeding women. Do not use this supplement if you have any underlying medical conditions

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The statements on this page have not been evaluated by the FDA. The products on this page are not intended to diagnose, treat, cure, or prevent any disease.
April 23, 2023
Cynthia R.
Citicoline Sodium Powder

Meditating easier and longer. I appreciate this product.

September 9, 2022
Adrian McMullan
Citicoline Sodium Powder

I am never disappointed with the results I receive when using LiftMode products. Thank you.

June 12, 2020
Citicoline Sodium Powder

I bought this and it did seem to help, enough that I am buying a larger size to see what happens over the course of a longer period of time. After my first dose I fell asleep and I'm thinking it's because I hadn't had enough sleep. I don't know if this helped relax me or not but I'm giving it the credit.

Serving size is 250 mg. As a dietary supplement, take 1-2 servings up to 3 times per day. Please start with the lowest suggested single serving quantity to assess response.

Supplement Facts

Serving size: 250mg
Servings per container:
Amount per serving: % DV

Citicoline Sodium (CDP Choline)

250 mg
LiftMode offers a variety of unit sizes of HPLC-tested Citicoline Sodium Powder, including a a 5g unit, a 20g unit, a 50g unit, a 100g unit and a 1kg unit. Our Citicoline Sodium Powder is of the highest quality.
Store securely in a dry cool location away from direct sunlight. Keep out of reach of children and pets. Do not take this or any other supplement, and instead consult doctor about use, if you are under the age of 18, pregnant or breastfeeding, taking prescription or OTC / nonprescription drugs, or if you have any known or suspected medical conditions. Do not use if product safety seal was damaged or missing upon receipt.
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Gluten Free
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Scientifically Tailored Ingredients

Citicoline (or CDP-Choline) is an endogenous compound that is found in several biochemical pathways in the human body.

When used as a dietary supplement, Citicoline can act as a powerful support for memory, neuroplasticity, focus, and a good mood.

* Memory Support
* Boosts Focus
* Promotes Learning

Secades, J. J. (2011). Citicoline: pharmacological and clinical review, 2010 update. (Article in English, Spanish). Rev Neurol. 52 Suppl 2:S1-S62.

Grieb, P., Jünemann, A., Rekas, M., Rejdak, R. (2016). Citicoline: A Food Beneficial for Patients Suffering from or Threated with Glaucoma. Frontiers in Aging Neuroscience. 2016;8:73

Weiss, S. B.. (1995). Metabolism and actions of CDP-choline as an endogenous compound and administered exogenously as citicoline. Life Sci. 56(9):637-60.

López-Coviella, I., Agut, J., Savci, V., Ortiz, J. A., Wurtman, R. J. (1995). Evidence that 5′-cytidinediphosphocholine can affect brain phospholipid composition by increasing choline and cytidine plasma levels. J Neurochem. 65(2):889-94.

Hurtado O, Mora, M. A., Cardenas, A., Sanchez, V., Fernández-Tomé, P., Leza, J. C., Lorenzo, P., Secades, J. J., Lozano, R., Dávalos, A., Castillo, J., & Lizasoain, I. (2005). Neuroprotection afforded by prior citicoline administration in experimental brain ischemia: effects on glutamate transport. Neurobiol Dis; 18(2):336-45.