Apigenin Powder

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Matricaria chamomilla, commonly known as German chamomile or Water of Youth, is a daisy looking flower and member of the Asteraceae family. The key active constituent present in the herb is apigenin, a flavonoid that is believed to contribute to chamomile’s antioxidant effects.

Apigenin Extract (Matricaria chamomilla) Benefits and Uses

Matricaria chamomilla is an annual flower and ancient medicinal plant. The dried flowers of chamomile are commonly used in medicinal teas and tinctures for thousands of years.

Today, Matricaria chamomilla is an extensively utilized medicinal plant with numerous pharmacological properties. Chemically, Matricaria chamomilla possesses phytochemical compounds with potent bioactive effects, which include terpenoids and flavonoids. The key active component is Apigenin, a flavone that is present in a number of vegetables such as parsley, and celery is shown to have important health-promoting effects. These included supporting the immune system and to support gastrointestinal health.

Anecdotally, Matricaria chamomilla has perceived antioxidant effects. One study tested its antioxidant status by analyzing the phytochemical composition and free radical savaging power of the methanol extract of the plant. The samples in the study showed Matricaria chamomilla exhibited significant antioxidant activities due to the presence of phenolic compounds and flavonoids. Furthermore, the study found that herb had no adverse effects on the liver (i.e. no hepatotoxicity). Moreover, Matricaria chamomilla may have skin health-promoting properties.

Scientific Consensus

Apigenin supplements are generally considered safe and non-toxic as per the reported cytotoxicity assessments.

However, Apigenin is likely unsafe for individuals with ragweed allergies. *Matricaria chamomilla * belongs to the same family as ragweed and individuals with ragweed allergies can have allergic reactions such as rashes and in high doses can cause nausea. Avoid use if you have any ragweed or chamomile allergies.

There is not enough data to say whether Apigenin is safe for pregnant or breastfeeding women, or if it can be used by children.

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The statements on this page have not been evaluated by the FDA. The products on this page are not intended to diagnose, treat, cure, or prevent any disease.
July 2, 2021
Apigenin Powder

This is my fifth time buying this product,we like it very much and feel very good !

May 21, 2021
Apigenin Powder

Stacks well with other calming LM stuff. Good with baicalein, or theanine for calming and winding down without dulling or slowing the mind

As a dietary supplement, take 1 serving up to 3 times per day. Please start with the lowest suggested single serving quantity to assess response.

Supplement Facts

Serving size: 250mg
Servings per container:
Amount per serving: % DV

ApigeninMatricaria chamomilla extract[Std. to ≥98% Apigenin]

LiftMode offers a variety of unit sizes of HPLC-tested Apigenin Powder, including a a 2g unit, a 5g unit, a 10g unit and a 20g unit. Our Apigenin Powder is of the highest quality.
Store securely in a dry cool location away from direct sunlight. Keep out of reach of children and pets. Do not take this or any other supplement, and instead consult doctor about use, if you are under the age of 18, pregnant or breastfeeding, taking prescription or OTC / nonprescription drugs, or if you have any known or suspected medical conditions. Do not use if product safety seal was damaged or missing upon receipt.
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Scientifically Tailored Ingredients

Apigenin possesses antioxidant, cognition enhancing, and relaxing properties through a variety of mechanisms shared by similar flavonoids like Baicalein. Some studies indicate it may be especially beneficial for promoting a healthy gut.

The calming effect of Apigenin is partially due to its ability to bind the GABA-A receptor and act as a partial modulator. It likely potentiates (and is potentiated by) other flavonoids due to its complex CYP enzyme interactions in the liver. Apigenin also is known for its mood-boosting effects and some studies indicate it may normalize the ERK/CREB/BDNF pathway and enhance BDNF expression in certain cases.

– Calming and stress-reducing
– Promotes healthy sleep
– Supports a positive mood

Haghi, G., Hatami, A., Safaei, A., & Mehran, M. (2014). Analysis of phenolic compounds in Matricaria chamomilla and its extracts by UPLC-UV. Research in pharmaceutical sciences, 9(1), 31–37.

Srivastava, J. K., & Gupta, S. (2009). Extraction, Characterization, Stability and Biological Activity of Flavonoids Isolated from Chamomile Flowers. Molecular and cellular pharmacology, 1(3), 138.

Miguel FG, Cavalheiro AH, Spinola NF, et al. Validation of a RP-HPLC-DAD Method for Chamomile (Matricaria recutita) Preparations and Assessment of the Marker, Apigenin-7-glucoside, Safety and Anti-Inflammatory Effect. Evid Based Complement Alternat Med. 2015;2015:828437. doi:10.1155/2015/828437.

Srivastava, J. K., Shankar, E., & Gupta, S. (2010). Chamomile: A herbal medicine of the past with bright future. Molecular medicine reports, 3(6), 895–901.

Tang D, Chen K, Huang L, Li J. Pharmacokinetic properties and drug interactions of apigenin, a natural flavone. Expert Opin Drug Metab Toxicol. 2017;13(3):323-330. doi:10.1080/17425255.2017.1251903