Matrine Powder

Unit Size

Want a discount? Become a member!


Sophora flavescens, often referred to as Ku Shen Gen or bitter root, is a well-regarded herb in traditional Chinese medicine with antioxidant and neuroprotective effects. The alkaloid Matrine is one of the main constituents in the plant. It has the chemical formula C15H24O2 and a molecular weight of 264.36 g/mol.

Matrine Benefits and Uses

Matrine is a water-soluble alkaloid extracted from Sophora flavescens, an evergreen shrub that grows in tropical climates. It is a popular nutraceutical and is commonly taken to improve immune function and support liver health.

Sophora flavescens has been used as a herbal remedy in traditional Chinese medicine for many centuries. Sophora flavescens possesses over 16 bioactive compounds, of which the most prominent is the alkaloid matrine and its related compounds oxymatrine and sophoridine. Matrine is also found in other plant species of the Sophora family.

Anecdotally, Matrine may offer some important immune and circulatory system-supporting benefits. Matrine also promotes restful sleep and relaxation.

Scientific Consensus:

Matrine extract is considered safe and effective when taken at the recommended serving size. There is not enough data to say whether Matrine is safe for pregnant or breastfeeding women, or if it can be used by children.

Read More
The statements on this page have not been evaluated by the FDA. The products on this page are not intended to diagnose, treat, cure, or prevent any disease.
January 27, 2023
Adam Bilbrey
Matrine Powder

This product has the potential to change lives. Esp if u are dependent on a certain family of meds for your pain needs, but are tired of feeling down and out or sick wen that chemical is not in ur body. I went 3 days without and this product kept me from being very sick. I couldn't believe it

Serving size is 250 mg. As a dietary supplement, take 1 servings up to 3 times per day. Please start with the lowest suggested single serving quantity to assess response.

Supplement Facts

Serving size: 250mg
Servings per container:
Amount per serving: % DV

Matrine(Sophora flavescens extract)

250 mg
LiftMode offers a variety of unit sizes of HPLC-tested Matrine Powder, including a a 2g unit, a 5g unit, a 10g unit and a 20g unit. Our Matrine Powder is of the highest quality.
Store securely in a dry cool location away from direct sunlight. Keep out of reach of children and pets. Do not take this or any other supplement, and instead consult doctor about use, if you are under the age of 18, pregnant or breastfeeding, taking prescription or OTC / nonprescription drugs, or if you have any known or suspected medical conditions. Do not use if product safety seal was damaged or missing upon receipt.
Read More
Free from additives and fillers
Gluten Free
HPLC Lab tested
Money back guarantee
Science backed

Scientifically Tailored Ingredients

Matrine is a naturally-occurring alkaloid found in *Sophora flavescens*. This herb is used in Traditional Chinese Medicine and is believed to support liver function. It has immune-modulating properties, and more recent studies indicate it is a potent antioxidant.

– Antioxidant
– Immune support
– Supports a health liver

National Center for Biotechnology Information (2020). PubChem Compound Summary for CID 114850, Oxymatrine. Retrieved August 18, 2020 from

Wang H, et al. (2012) Comparative analysis of quinolizidine alkaloids from different parts of Sophora alopecuroides seeds by UPLC-MS/MS. J Pharm Biomed Anal.

Li K, Wang H. (2004) Simultaneous determination of matrine, sophoridine and oxymatrine in Sophora flavescens Ait. by high performance liquid chromatography. Biomedical Chromatography, 18(3):178-82.

Yuan Jing, Zhang Zong-jian, Cong Bin. Biological activity of matrine and its research progress. Pesticides. 2003;42(7):1–4.

Lee, H. J., Lee, S. Y., Jang, D., Chung, S. Y., & Shim, I. (2017). Sedative Effect of Sophora flavescens and Matrine. Biomolecules & Therapeutics, 25(4), 390–395.