Agmatine is a newly understood neurotransmitter that is produced from L-Arginine. It is synthesized in the brain and stored in synaptic vessels for use in receptor signaling pathways. Agmatine has the chemical formula C5H14N4 and a molecular mass of 130.195 g/mol.
Agmatine Sulfate Benefits and Uses
Agmatine Sulfate is an amino acid derivative that has recently been discovered to act as a neurotransmitter. It has been used in research for analgesic and neuroprotective effects. It works primarily as an NMDA receptor antagonist, an alpha-2-adrenergic receptor activator, and a serotonin signal enhancer. It also helps regulate nitric oxide production and may block Ca2+ and K+ channels.
Agmatine Sulfate is known by a number of alternative names, including:
- 1-(4-Aminobutyl)guanidine
- Agmatin
- Agmatine Sulfate
Scientific Consensus
Agmatine is a naturally-occurring chemical found in plant species, animals, and humans. It is made from L-arginine. Agmatine sulfate is considered possibly safe for use by most people at the recommended serving size.
There is still a need for further research to properly understand the significance of its benefits and adverse effects. Some people have reported experiencing diarrhoea, upset stomach, and nausea.
Warning: There is not enough research about the safety of Agmatine for pregnant and breastfeeding women. Do not use this supplement if you have any underlying medical conditions – especially people with diabetes, or undergoing surgery.