Nicotinamide Riboside, also known as Niagen or NR, is an alternate form of Vitamin B3 or Niacin. NR and Niacin are precursor vitamins for nicotinamide adenine dinucleotide (NAD+). It has the chemical formula C11H15N2O5+ and a molecular weight of 255.25 g/mol.
Nicotinamide Riboside (NR) Benefits and Uses
Nicotinamide Riboside is easily and sustainably converted into NAD+, a coenzyme that is vital to many biological processes in the body such as the repair of DNA, boosting immune response, converting food into energy and regulating circadian rhythms.
Anecdotally, increased NAD+ levels through Nicotinamide Riboside supplementation may be associated with many health benefits. NAD+ has perceived abilities to enhance mitochondrial respiration as well as cognitive function.
Nicotinamide Riboside supplements are also known by a few different names, including:
- Niagen
- Vitamin B3
- Niacinamide
- Niacin
- N-Ribosylnicotinamide
- 1-(β-D-Ribofuranosyl) nicotinamide
- NAD
- NR
- Nicotinamide Adenine Dinucleotide
Scientific Consensus
Nicotinamide Riboside supplements are considered safe even at large serving sizes. Dosages of 1000-2000mg have been safely administered for periods of 8 weeks.
Nicotinamide Riboside supplements may cause mild and moderate side effects such as nausea, headaches and diarrhea. Currently, there isn’t enough information regarding the safety of Nicotinamide Riboside for pregnant or breastfeeding women, or if it can be used by children