A powerful nootropic and cellular support compound, Oroxylin A is a flavonoid naturally produced in several plant species, but is most concentrated in the Indian trumpet tree species Oroxylum indicum. It has the chemical formula C16H12O5 and a molecular weight of 284.26 g/mol. It has also been used historically in traditional Ayurvedic medicine to soothe joints and digestive upset, among other documented uses.
Anecdotally, Oroxylin A is used to boost productivity, curb stress, and help overcome attention displacement. As a powerful tool for boosting focus, Oroxylin A is considered an ideal natural nootropic to take before exams, creative work sessions, or alongside an energizing morning routine.
While the few sources that can be found on the market commonly range from 0-10% purity, LiftMode’s Oroxylin A powder is one of the most potent available with a ≥98% purity verified by third-party HPLC-testing and is highly active in small amounts. As with most concentrated nootropic compounds, we recommend starting with a small serving size to assess its effects before committing to a full serving size.
Oroxylin A Benefits and Uses
Oroxylin A has been extensively clinically studied for its beneficial effects on cognition, heart health, oxidative stress, healthy aging, immune support, liver health, and mood. Oroxylin A is also thought to have activity on dopamine levels (by increasing them) and to act as a negative allosteric modulator of the GABA-A receptor.
Cognition and Focus
Oroxylin A has been found to be one of the most effective nootropic compounds available to the general public. Several recent studies show supporting evidence that Oroxylin A may help to enhance cognition and memory. Human studies further suggest that Oroxylin A may offer neuroprotective properties as a potent antioxidant.
Healthy Aging and Stress Resilience
Evidence suggests that Oroxylin A supports healthy skin by reducing oxidative stress caused by sun damage. It can also help to maintain a balanced circulatory system and shows promise in several studies as a powerful compound for liver support.
Brain-derived neurotrophic factor and memory enhancement
In animal trials, Oroxylin A was found to enhance memory consolidation through the brain-derived neurotrophic factor.
Oroxylin A is known by a number of alternative names, including:
- Indian trumpet flower
- Sabroxy
- Oroxylum
- Tree of Damocles
Scientific Consensus
There is not enough research about the safety of Oroxylin A for pregnant and breastfeeding women. Do not use this supplement if you have any underlying medical conditions. Please consult your healthcare provider before use if you have a medical condition or if you are taking any prescription medications. Not for use by people under the age of 18, by pregnant or nursing women, or for those with a medical condition.