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One of a kind capsules, combining natural ingredients to provide mildly energizing physical and mental boost. MoodLift is the ideal supplement stack for those seeking a daily natural, caffeine free, boost to mood, energy and wellbeing. Seize the Day with Moodlift.

The 20 vitamins, minerals, nutrients, biochemical precursors, and plant extracts work in unison to produce a dynamic mood-enhancing, stress-reducing and gently energizing effect, and were developed using our Three Pillar methodology:

Pillar 1: Calming and Stress Reducing Plant Extracts

The first pillar contains a combination of five naturally occurring herbal extracts known to help to reduce feelings of stress, while providing a gentle calming and relaxing effect – mostly through effects on the GABAergic system.

Magnolol (Magnolia Bark Extract) (28 mg) is the active compound found in the bark of the Houpu magnolia plant and has relaxing (although not sedating) GABAergic activity with added health benefits.

Baicalein (Blue Skullcap Extract) (60mg) is one of active biochemical compounds found in the root of the native American plant, Scutellaria baicalensis and is used primarily for its antioxidant and anti-inflammatory properties, along with its calming, stress-reducing benefits.

Piperine (Black Pepper Extract) (6 mg) is a potent PGP and CYP enzyme inhibitor that temporarily inhibits Glucuronidation (the ‘tagging’ of foreign substances by immune cells), allowing improved bioavailability of biochemical compounds; also known for its mood-supporting effects.

Sinomenium acutum Extract (36 mg) has been used traditionally for its neuroprotective, anti-inflammatory and analgesic properties; also for its PGP inhibitor effects to increase bioavailability of other compounds.

Gotu Kola Extract (28 mg) is an adaptogen and natural Nootropic, well-known for its potent relaxing effects. The primary active components of Gotu Kola are triterpenoid saponins Asiaticoside, Asiaticoside B, and Madecassoside, which have strong mood-enhancing, relaxing, and anti-inflammatory effects.

Pillar 2: Synergistic Energizing Vitamins, Nutrients, and Plant Extracts 

The second pillar of MoodLift consists of a combination of 6 herbal extracts and vitamins, uniquely combined in the perfect synergistic ratio to provide a gentle energizing effect, without a crash afterwards.

Vitamin B12 (600 mg) is a water soluble vitamin that plays an essential role in the production of red blood cells (essential for optimal energy levels), immune function and improved memory. It, along with vitamin B6 and B1, is essential for monoamine neurotransmitter production.

Vitamin B6 (as Pyridoxine HCl) (3 mg) is a water soluble vitamin that plays an important role specifically in protein metabolism, production of healthy blood cells for energy as well as supporting healthy cognition and mood.

Benfotiamine (28 mg) is a synthetic precursor of Vitamin B1, also known as Thiamine. Thiamine plays an important role in helping our bodies convert food into energy, and is recognised for its beneficial effects in supporting nerve, muscle, and heart function.

Folate (0.6 mg) is a form of vitamin B9 and an essential component of DNA repair. It is also used to help synthesize red blood cells and convert carbohydrates into cellular energy.

7,8-DHF (Dihydroxyflavone) (36 mg) is a naturally-occurring compound, believed to support learning and reduce mental fatigue by directly binding to the tropomyosin-related kinase B (TrkB) and enhancing TrkB expression, thereby improving the rate at which new synapses are formed.

Ginseng (Panax ginseng) (56 mg) is a herbal physical and cognitive adaptogen that has been used in Traditional Chinese Medicine (TCM) for centuries. It contains natural powerful ginsenosides that are responsible for this supplement’s beneficial effects on physical energy levels and mental focus.

Pillar 3: Natural Extracts and Biochemical Precursors for Catecholamine Care

The Third Pillar consists of a combination of natural extracts and biochemical precursors that work collectively to gently enhance mood: by activating the catecholamine system and/or improving the brain’s natural production of serotonin – an important monoamine neurotransmitter known widely for its effects on mood. The catecholamine system supports the body’s response to stress and is regulated by epinephrine (adrenaline), norepinephrine (noradrenaline), and dopamine.

Barley Malt Extract (18 mg) is a dietary supplement that is related to tyramine and contains high concentrations of Hordenine HCI (standardized to 98%). Hordenine HCl is a gentle, naturally-occurring MAOI that boosts catecholamine levels to support mental and physical energy and a positive mood.

Rhodiola Rosea (56 mg) is used for its perceived effects in increases our body’s resistance to stress. It is a physical and cognitive adaptogen that is traditionally used to reduce fatigue, while also supporting catecholamine levels.

Triacetyluridine (TAU) (18 mg) is a biochemical precursor to the nucleoside Uridine. Uridine plays an important role in cellular signalling, specifically in our brains. It is best-known for its positive effects on cognitive function, memory and mood, and helps support healthy dopamine and CDP-Choline levels.

Oroxylin A (18 mg) is one of the main flavonoid compounds found in the root of the Oroxylin indicum plant and is known primarily for its antioxidant and anti-inflammatory properties. It is also known to boost levels of catecholamine transmitters like dopamine and norepinephrine. Oroxylin A has demonstrated therapeutic effects in improving stress, sleep quality and memory by stimulating gamma-aminobutyric acid (GABA-A) receptors.

Citicoline (CDP-Choline) (28 mg) is a naturally-occurring compound produced through several biochemical systems in the human body. It is metabolized into Choline and Cytidine, which are then used to resynthesize CDP-Choline in the brain. CDP-Choline is best-known as a cognitive support supplement to help promote health cognitive performance and memory. Studies have shown that it may be effective in supporting focus, attention and learning.

Pillar 4: Potent Mood Enhancing Biochemical Compounds

The Fourth Pillar of MoodLift is comprised of four plant extracts and biochemical precursors that were carefully selected for their capacity to work in unison and provide a gentle serotonin boosting effect. Serotonin has long been known for its beneficial effects on supporting a positive mood and outlook.

Kanna (Sceletium tortuosum) (28 mg) is a well-known and increasingly popular plant extract used for its effects in producing a relaxed yet cheerful mood. Often used to improve sociability, Kanna works by boosting levels of the neurotransmitters Serotonin and Norepinephrine.

Peony Root extract (38 mg) also known as Paeonia lactiflora Pall, is a novel plant extract that supports a positive mood by reducing the expression of serotonin transporter (SERT): a protein that binds to serotonin so it can be broken down and recycled. Inhibiting SERT prevents this process, thus increasing serotonin levels to produce a temporary mood enhancing effect.

5-HTP (28 mg) is an amino acid precursor to the important neurotransmitter serotonin. It is also known to support a positive mood and promote healthy sleep.

THH (Tetrahydroharmine) (18 mg) is a component of B.caapi, used for its effects in regulating motivation and overall mood. THH has a half-life of 10 hours and acts as an inhibitor of a specific enzyme called monoamine oxidase A (MAO-A), which regulates the functioning of two important neurotransmitters dopamine and serotonin. It is also unique in potentially being able to support adult neurogenesis.

This product contains 60 delayed-release capsules of MoodLift in a high quality white, reclosable plastic capsule jar with an integrated Safety Seal and Shrinkband. A single serving is 2 capsules.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Do not take this supplement if you are under the age of 18, pregnant or nursing, or have a known or suspected medical condition. Do not combine with prescription antidepressants or MAOIs. Do not take within 3 hours of any prescription medications.

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The statements on this page have not been evaluated by the FDA. The products on this page are not intended to diagnose, treat, cure, or prevent any disease.

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Serving size is 1 capsule. As a dietary supplement, take 1-2 servings per day. Do not combine with prescription medications. Please start with the lowest suggested single serving quantity to assess response.

Supplement Facts

Serving size: 1 capsule
Servings per container:
Amount per serving: % DV

Levomefolic Acid Calcium Salt (bioavailable form of Folic Acid)

10 mg
4250%

Pyridoxal 5 Phosphate (bioavailable form of Vitamin B6)

3 mg
176

Vitamin B12 (as Mecobalamin)

300 mcg
12,500%

Arctic Root Extract [≥5% Rosavins, ≥2% Salidroside] (Rhodiola rosea)

32 mg

Ginseng Root Extract Blend [≥30% Ginsenosides] (Panax ginseng*& *Panax notoginseng]

32 mg

7,8-Dihydroxyflavone (from Tridax Daisy aerial parts] [≥98% 7,8-DHF](Tridax procumbens)

24 mg

Sinomenium accutum Stem Extract [≥98% Sinomenine HCL]

21 mg

Peony Root Extract [≥50% Albiflorin/Paeoniflorin] (Paeonia officialis ´rubra plena`]

25 mg

Baicalein(from Baikal Skullcap Root Extract) [≥98% Baicalein] (Scutellaria baicalensis)

16 mg

Benfotiamine (Bioavailable form of Vitamin B1)

16 mg

Citicoline (CDP-Choline)

16 mg

5-Hydoxytryptophan (5-HTP)

16 mg

Magnolol (from Magnolia Bark Extract) [≥98% Magnolol] (Magnolia officinalis)

16 mg

Gotu Kola Aerial Parts Extract [≥70% Triterpenoids] (Centella asiatica)

18 mg

Oroxylin A (from [Tree of Domocles bark extract) [98% Oroxylin A] (Oroxylum indicum)

13 mg

Triacetyluridine (TAU) (bioavailable form of Uridine)

13 mg

Tetrahydroharmine (THH)

10 mg

Kanna Aerial Parts Extract [≥5% Alkaloids, ≥3% Mesembrine] (Sceletium tortuosum)

16 mg

Piperine (from Black Pepper Fruit Extract) [≥95% Piperine] (Piper nigrum)

3 mg
Delayed Release HPMC Veggie Capsules
Store securely in a dry cool location away from direct sunlight. Keep out of reach of children and pets. Do not take this or any other supplement, and instead consult doctor about use, if you are under the age of 18, pregnant or breastfeeding, taking prescription or OTC / nonprescription drugs, or if you have any known or suspected medical conditions. Do not use if product safety seal was damaged or missing upon receipt.
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Scientifically Tailored Ingredients

Levomefolic acid calcium salt, commonly known as L-methylfolate or 5-MTHF, is the active form of folate, a B-vitamin crucial for various bodily functions. Unlike regular folic acid, which needs to be converted into its active form (5-MTHF) by the body before it can be utilized, levomefolic acid is already in its bioavailable form, ensuring superior absorption and utilization.

Involved in various bodily functions, such as aiding in DNA synthesis, neurotransmitter production (such as serotonin, dopamine, and norepinephrine), and regulating homocysteine levels, levomefolic acid may help to support to improved energy, enhanced cognition, better mood stability, and overall mental wellness.

Pyridoxal 5-phosphate (PLP) is the active form of vitamin B6 and plays a crucial role in various physiological processes in the body. Unlike regular vitamin B6 (pyridoxine), PLP does not require additional conversion in the body, making it readily usable and easily absorbed. Its bioavailability contributes significantly to supporting enzymatic reactions involved in metabolism, neurotransmitter synthesis (like serotonin and dopamine), and the regulation of amino acids. PLP’s presence is vital for energy metabolism, aiding in the breakdown of carbohydrates, fats, and proteins, which helps sustain energy levels. Moreover, it supports cognitive function, nervous system health, and contributes to overall well-being by facilitating various biochemical reactions essential for optimal health.

Vitamin B12, also known as cobalamin, is a water soluble vitamin that plays an essential role in growth and development, the production of red blood cells (essential for optimal energy levels), immune function and improved memory. Vitamin B12 is found exclusively in foods of animal origin. Individuals following a vegetarian diet are therefore at an increased risk for dietary vitamin B12 deficiency..

– Enhances Energy
– Supports Healthy Immune Function
– Boosts Memory

Rhodiola rosea is an herbal extract used as an ingredient in dietary supplement products. It is said to prevent stress and fatigue, while also acting as a powerful antioxidant and to improve cognitive performance.

– Balances Stress
– Boosts Cognition
– Powerful Antioxidant

Berberine is a compound that can be extracted from a number of herbs and plants. It has a history of use in traditional Chinese medicine and was once used as a treatment for diarrhea. Berberine is a highly effective dietary supplement with a number of remarkable health benefits. It is especially beneficial for use by diabetics and people with high cholesterol, who are at risk of developing diabetes.

* Promotes a Healthy Circulatory System
* Supports Strong Metabolism

7,8-DHF (7,8-Dihydroxyflavone) is a naturally occurring flavonoid with possible cognition-enhancing properties. Its recent discovery has spurred research into its unique properties.

By enhancing TrkB expression, 7,8-DHF may help to increase the rate new synapses are formed, thus enhancing learning. Some researchers hypothesize that 7,8-DHF does not bind TrkB directly, but instead acts on an unknown pathway that results in the same end result–increased TrkB activity. 7,8-DHF is believed to have a similar degree of neurogenic activities as BDNF.

On top of its effects on neurogenesis, 7,8-DHF is also neuroprotective. It has antioxidant properties in the brain that are independent of its TrkB activity. While these mechanisms are not understood, it is believed to activate the Akt/PKB pathway.

* Supports Healthy Memory and Focus
* May Promote Adult Neurogenesis
* Neuroprotective and Antioxidant

Sinomenine is the active compound in the roots of the *Sinomenium acutum* plant. As a herbal extract, Sinomenium acutum has been used traditionally for its neuroprotective properties. Research suggests it assists in increasing the influx of chloride into the cells of the hypothalamus – a small part of the brain that plays an important role in energy maintenance and in stress control.

– Mood Lifting
– Potent Neuroprotective Properties
– Supports Immune Function

Peony root, also known as *Paeonia lactiflora Pall*, is a flowering plant known for its stress reducing and mood boosting properties. Research suggests that Peony Root extract supports a positive mood by reducing the expression of serotonin transporter (SERT) – a protein that binds to serotonin so it can be broken down and recycled. Inhibiting SERT prevents this process, which increases serotonin levels, thus producing a mild mood-enhancing effect.

– Boosts Serotonin Levels
– Supports a Positive Mood
– Antioxidant Properties

Baicalein is the primary active component from the Blue Skullcap plant (also known as Baikal Skullcap). This powerful phytochemical is known to act on GABA receptors to promote relaxation and relieve stress. Baicalein also acts as a strong antioxidant supplement and helps to promote a healthy circulatory system.

• Calming and Stress-Reducing
• Antioxidant and Immune Support
• 5 – 10x Bioavailability Compared to Baicalin

Benfotiamine is a synthetic form on the vitamin Thiamine (vitamin B1). Once absorbed, Thiamin gets converted into the active form. Research suggests that Thiamin plays an important role in helping our bodies turn food, especially carbohydrates into energy. Due to its essential role in providing our bodies cells with energy, it plays a key role in nerve, muscle, and heart function.

– Facilities Energy Metabolism
– Boosts Energy Levels
– Supports Healthy Nerve Function

Citicoline (or CDP-Choline) is an endogenous compound that is found in several biochemical pathways in the human body.

When used as a dietary supplement, Citicoline can act as a powerful support for memory, neuroplasticity, focus, and a good mood.

* Memory Support
* Boosts Focus
* Promotes Learning

5-HTP is an amino acid precursor to the neurotransmitter serotonin. It has been said to support positive mood, reduce cravings, and promote healthy sleep.

* Uplifts Mood
* Precursor to Serotonin
* Promotes Healthy Sleep

Magnolol is compound found in *Magnolia officinalis* (also known as Magnolia Bark) and is known to be a powerful antioxidant.

In addition to protecting cells from potentially harmful free radicals, Magnolol can also be used to promote respiratory health.

– Improves Brain Health
– Promotes Relaxation
– Powerful Immune Support

Gotu Kola (Centella asiatica) is a perennial found in marshes throughout most of Asia. The primary active components of Gotu Kola are triterpenoid saponins Asiaticoside, Asiaticoside B, and Madecassoside, which have potent mood lifting, relaxing, and anti-inflammatory effects.

Traditionally, Gotu Kola is used for stress and mood, but recent studies indicate the triterpenoid saponins may have a more complex role than expected. Gotu Kola increases cerebral GABA levels, which is the primary inhibitory neurotransmitter. The saponins have been shown to increase serotonin, dopamine and norepinephrine levels in the brain.

Gotu Kola may also have long-term benefits. The saponins and their metabolites are believed to promote neurogenesis by enhancing expression of BDNF (Brain Derived Neurotrophic Factor) and NGF (Nerve Growth Factor) which may promote learning as well as mood.

– Promotes Mental Clarity
– Calming and Stress Relief
– Neuroprotective Benefits

Oroxylin A is a unique and cutting-edge plant compound, and of the primary flavonoids of *Scutellaria baicalensis* (Blue Skullcap). Flavones are active compounds known primarily for their antioxidant properties. The flavonoid compound Oroxylin A, is recognized today for its therapeutic effects in improving symptoms of stress, enhancing catecholamine production, and supporting memory.

– Boosts Levels of Catecholamines Dopamine and Norepinephrine
– Antioxidant Properties
– Unique and Cutting-Edge Plant Extract

Triacetyluridine is a naturally-occurring compound and precursor to the nucleoside Uridine (pictured to the left). Uridine plays an important role in cellular signaling, and supports both CDP-Choline and dopamine levels in the brain. For this reason, Triacetyluridine is becoming a sought after dietary supplement for its perceived effect in boosting cognitive function, memory and mood.

– Promotes Healthy Memory and Cognition
– Potent Neuroprotective Benefits
– Supports a Positive Mood

Tetrahydroharmine (THH) is one of a family of β-carboline (indole-related) harmala alkaloids, found in the Banisteriopsis caapi (yagé, or ayahuasca) vine and related species, as well as in Peganum harmala (which lends these alkaloids their “harmala alkaloid” nomenclature).

Scientific research has revealed that (±)-Tetrahydroharmine functions as a mild serotonin reuptake inhibitor, and one isomer may also have gentle weak reversible MAOI activity (much less potent than that of Harmaline or Harmine), allowing for synergies with other natural phytochemicals that may be deactivated by MAO, including indole derivatives.

In addition, THH has nootropic potential. Studies suggest that the neuroprotective β-carboline harmala alkaloids from the Banisteriopsis caapi vine, including THH, uniquely promote adult neurogenesis. The combination of bioactivities in THH may help support healthy serotonin levels and promote a positive and open mood.

– Supports Healthy Mood
– Helps Manage Stress
– Powerful Neuroprotective

Kanna is a succulent plant within the *Aizoaceae* family and has been used for its mood-enhancing properties by humans in South Africa since the Stone Age. *Sceletium tortuosum* based products include a wide variety of different extracts. LiftMode’s MT55 Kanna extract based products are produced with one of the most potent and high-quality Kanna extracts available.

Kanna extracts are reputed to produce tranquil yet cheerful states of mind while acting as a mild stress-reducing SRI (serotonin reuptake inhibitor). Kanna extracts have also been known to enhance cognitive function and reduce nicotine cravings.

– Boosts Mood
– Reduces Stress
– Promotes Tranquility

Piperine is an alkaloid extracted from black pepper and is typically used for its ability to inhibit the process of glucuronidation. This allows for significantly increased absorption of many types of dietary supplements.

– Antioxidant Effects
– Slows the Degradation of Polyphenols
– Improves Ingredient Bioavailability

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